Low-Calorie, Fasting-Mimicking Diet May Benefit Those With Crohn's Disease

**Improving Crohn's Disease Symptoms with Fasting-Mimicking Diet** A recent study published in Nature Medicine suggests that a fasting-mimicking diet may be beneficial for individuals living with Crohn's disease.

**Improving Crohn's Disease Symptoms with Fasting-Mimicking Diet**

A recent study published in Nature Medicine suggests that a fasting-mimicking diet may be beneficial for individuals living with Crohn's disease. The research, conducted at Stanford University, involved 97 participants and found that those who followed the diet experienced significant improvements in symptoms and biological indicators of the disease.

**A Calorie-Deficit Approach**

The study involved a short-term calorie-restricted diet, where participants consumed between 700 and 1,100 calories per day for five consecutive days out of every month for three consecutive months. This approach was found to improve symptoms in two-thirds of those who followed the fasting-mimicking diet.

**Reducing Gut Inflammation**

Biological indicators of disease were also significantly improved among participants who followed the fasting-mimicking diet. These included reduced levels of calprotectin protein in stool, indicating less gut inflammation, and lower production of inflammatory molecules by immune cells.

**Expert Insights**

"We were very pleasantly surprised that the majority of patients seemed to benefit from this diet," said Sidhartha R. Sinha, MD, an assistant professor of gastroenterology and hepatology at Stanford and senior author on the paper. "This study will give physicians evidence to support recommendations in an area that patients are very curious about."

**What This Means for You**

If you're living with Crohn's disease, this research may offer new hope for managing your symptoms. However, it's essential to consult with a healthcare professional before making any changes to your diet or treatment plan.

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